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Research

April 13, 2016
Zika Virus and Birth Defects - Reviewing the Evidence for Causality. NEJM (non-IHS.gov link)

New England Journal of Medicine
Rasmussen SA, Jamieson DJ, Honein MA, Petersen LR.  Special Report (Published online). 

Researchers note the evidence supporting the causal relationship between prenatal Zika virus infection and microcephaly and other serious brain anomalies.

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April 14, 2016
Update: Ongoing Zika Virus Transmission - Puerto Rico, November 1, 2015-April 14, 2016 (non-IHS.gov link)

Emilio Dirlikov, PhD; Kyle R. Ryff, MPH; Jomil Torres-Aponte, MS; et al.
MMWR Morb Mortal Wkly Rep 2016;65:(Early Release)

During November 1, 2015–April 14, 2016, a total of 6,157 specimens from suspected Zika virus–infected patients from Puerto Rico were evaluated, and 683 (11%) had laboratory evidence of current or recent Zika virus infection. Of the 683, there were 65 (10%) symptomatic pregnant women who tested positive for Zika. A total of 17 (2%) patients required hospitalization, including five patients with suspected Guillain-Barré syndrome. One patient died after developing severe thrombocytopenia. The public health response in Puerto Rico includes increased capacity to test for Zika virus, preventing infection in pregnant women, monitoring infected pregnant women and their fetus for adverse outcomes, controlling mosquitos, and assuring the safety of blood products.

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May 11, 2016
Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise (non-IHS.gov link)

Researchers at Washington University in St. Louis established the first models of Zika virus transmission from a pregnant mouse to her fetus.

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