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National Core Formulary

The IHS National Core Formulary represents the basic standard of care drugs which must be carried by all federal facilities to generally promote the parity, portability, quality, safety, convenience, and cost-effectiveness of the pharmacy benefit.

  • It establishes the "floor" for the pharmacy benefit.
  • Except in closed classes, facilities are expected to add other drugs to the local formulary as needed.
Last Updated: 02/24/2021
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The following is a list of Medications currently in the queue. 206 record(s) found.
The following is a list of Medications currently in the queue. 206 record(s) found.
MedicationPharmacological CategoryFormulary BriefNotesSimilar Medications
Acetaminophen Analgesic, Miscellaneous
Adalimumab -OR- Etanercept (can choose either product) Antirheumatic, Disease Modifying; Tumor Necrosis Factor (TNF) Blocking Agent TNF Inhibitors (2016) ONLY In consultation with a rheumatologist Etanercept -OR- Adalimumab (can choose either product)
Albuterol nebulized solution Beta2 Agonist
Albuterol, metered dose inhaler (MDI) Beta2 Agonist NPTC Meeting Update (Nov 2017) *Any product*
Alendronate Bisphosphonate Derivative Osteoporosis (2016)
Allopurinol Antigout Agent; Xanthine Oxidase Inhibitor Gout (2016)
Alogliptin Antidiabetic Agent, Dipeptidyl Peptidase 4 (DPP-4) Inhibitor DPP-IV Inhibitors (2019)
Amitriptyline Antidepressant, Tricyclic Antidepressants in Pain Mgmt (2014) Nortriptyline
Amlodipine Antihypertensive; Calcium Channel Blocker, Dihydropyridine Calcium Channel Blockers (2014) Diltiazem
Anastrozole Antineoplastic Agent, Aromatase Inhibitor
Angiotensin receptor blocker ===REMOVED from NCF=== (see Losartan) Angiotensin II Receptor Antagonists (2014) Removed April 2012 Losartan
Apixaban Anticoagulant; Direct Oral Anticoagulant (DOAC); Factor Xa Inhibitor Direct Oral Anticoagulants (2017) Warfarin
Aripiprazole lauroxil Antipsychotic, Atypical (Second Generation) - Injectable Long-Acting Injectable Antipsychotics (2020) Injectable Haloperidol decanoate
Aspirin Antiplatelet Agent; Nonsteroidal Anti-Inflammatory Drug; Salicylate
Atenolol Antihypertensive; Beta-Blocker, Beta1 Selective Beta Blockers (2014) Metoprolol; Propranolol
Atomoxetine Norepinephrine Reuptake Inhibitor, Selective ADHD (2020) Dextroamphetamine / Amphetamine (immediate release); Dextroamphetamine / Amphetamine (long-acting); Methylphenidate (immediate release); Methylphenidate (long-acting)
Atorvastatin Antilipemic Agent, HMG-CoA Reductase Inhibitor Dyslipidemia Guideline Review (2014) Pravastatin; Rosuvastatin; Simvastatin
Atypical antipsychotic Antipsychotic, Atypical Atypical Antipsychotic Agents (2015) *Any product* Aripiprazole lauroxil; Haloperidol decanoate
Benzoyl Peroxide Topical Skin Product, Acne Acne Treatment (2020) Benzoyl Peroxide AND Clindamycin, topical combination
Benzoyl Peroxide AND Clindamycin, topical combination Topical Skin Product, Acne; Topical Skin Product, Acne (Lincosamide Antibiotic) Acne Treatment (2020) Benzoyl Peroxide
Bictegravir/emtricitabine/tenofovir alafenamide Antiretroviral, Integrase Inhibitor (Anti-HIV) HIV Treatment (2019) Dolutegravir/abacavir/lamivudine; Emtricitabine/tenofovir disoproxil fumarate; Raltegravir
Buprenorphine (**REMS drug**) Analgesic, Opioid; Analgesic, Opioid Partial Agonist Opioid Use Disorder (2018) For treatment of Opioid Use Disorder in pregnant patients; **See REMS here** Exit Disclaimer: You Are Leaving www.ihs.gov 
Buprenorphine-naloxone (**REMS drug**) Analgesic, Opioid; Analgesic, Opioid Partial Agonist Opioid Use Disorder (2018) **See REMS here** Exit Disclaimer: You Are Leaving www.ihs.gov  Naloxone
Bupropion Antidepressant, Dopamine/Norepinephrine-Reuptake Inhibitor; Smoking Cessation Aid Nicotine Dependence (2015) Varenicline; Venlafaxine
Calcium Electrolyte supplement *Any formulation*
Carbamazepine Anticonvulsant, Miscellaneous Antiepileptics (2014) Divalproex; Lamotrigine; Levetiracetam; Phenytoin; Topiramate
Carbidopa-Levodopa (immediate release) Anti-Parkinson Agent; Decarboxylase Inhibitor-Dopamine Precursor Parkinson's Disease (2019)
Carvedilol Antihypertensive; Beta-Blocker with Alpha-Blocking Activity Beta-blockers in Heart Failure (2017) *Immediate-release only Atenolol; Metoprolol; Propranolol
Chlorthalidone Antihypertensive; Thiazide-Related Diuretic Diuretic Agents (2014) Hydrochlorothiazide
Citalopram Antidepressant, Selective Serotonin Reuptake Inhibitor SSRIs (2019) Escitalopram; Fluoxetine; Paroxetine; Sertraline
Clindamycin, topical ===REMOVED from NCF=== (See Benzoyl Peroxide AND Clindamycin, topical combination) Removed January 2020
Clonazepam Benzodiazepine Alcohol Withdrawal Syndrome (2015) Lorazepam
Clopidogrel Antiplatelet Agent Antiplatelets (2015) Aspirin
Conjugated estrogen vaginal cream, (Premarin) ===REMOVED from NCF=== (see Estrogen vaginal cream) NPTC Meeting Update (May 2018) Removed May 2018 Estrogen vaginal cream
Corticosteriods (Topical) - High potency (Class I and II) Topical Corticosteroids Psoriasis (2018) Corticosteroid (Topical) - Intermediate potency; Corticosteroid (Topical) - Low potency
Corticosteroid (Topical) - Intermediate potency Topical Corticosteroids *Any product* Corticosteriods (Topical) - High potency (Class I and II); Corticosteroid (Topical) - Low potency
Corticosteroid (Topical) - Low potency Topical Corticosteroids *Any product* Corticosteriods (Topical) - High potency (Class I and II); Corticosteroid (Topical) - Intermediate potency
Corticosteroid, intranasal Intranasal Corticosteroid *Any product*
Cyanocobalamin (Vitamin B12), oral Vitamin, Water Soluble Hematologic Supplements (2016)
Dedicated emergency contraceptive ===REMOVED from NCF=== (see Levonorgestrel; Ulipristal) Contraception (2016) Removed Sept 2013 Levonorgestrel (Plan B One-Step®); Ulipristal
Dextroamphetamine / Amphetamine (immediate release) Central Nervous System Stimulant Pediatric use only Dextroamphetamine and amphetamine (long-acting)
Dextroamphetamine / Amphetamine (long-acting) Central Nervous System Stimulant Pediatric use only Dextroamphetamine and amphetamine (immediate release)
Diclofenac Nonsteroidal Anti-Inflammatory Drug NSAIDs (2014) *Any formulation* Ibuprofen; Indomethacin; Meloxicam; Naproxen
Dicyclomine Anticholinergic Agent Irritable Bowel Syndrome (2018)
Digoxin Antiarrhythmic Agent, Miscellaneous; Cardiac Glycoside Digoxin Use (2016)
Diltiazem Antihypertensive; Calcium Channel Blocker, Nondihydropyridine Calcium Channel Blockers (2014) Amlodipine
Divalproex Anticonvulsant, Miscellaneous ER Lithium & Divalproex (2012) Carbamazepine; Lamotrigine; Levetiracetam; Phenytoin; Topiramate
Dolutegravir Antiretroviral, Integrase Inhibitor (Anti-HIV) HIV Updates (2020) For HIV treatment in pregnant patients Emtricitabine/tenofovir disoproxil fumarate; Raltegravir
Dolutegravir/abacavir/lamivudine Antiretroviral, Integrase Inhibitor (Anti-HIV) HIV Treatment (2019) *Note: HLA B5701 testing required prior to initiation Bictegravir/emtricitabine/tenofovir alafenamide; Dolutegravir; Emtricitabine/tenofovir disoproxil fumarate; Raltegravir
Donepezil Acetylcholinesterase Inhibitor (Central) 5mg and 10mg strengths
Doxazosin Alpha1 Blocker; Antihypertensive Benign Prostatic Hypertrophy (2016) Prazosin; Tamsulosin
Dulaglutide ===REMOVED from NCF=== NPTC Meeting Update (2020) Removed Nov 2020
Duloxetine Antidepressant, Serotonin/Norepinephrine Reuptake Inhibitor/Antagonist Diabetic Neuropathy (2018) Bupropion; Venlafaxine
Empagliflozin Antidiabetic Agent, Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor SGLT-2 Inhibitors (2019)
Emtricitabine/tenofovir disoproxil fumarate Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside (Anti-HIV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV) HIV Pre-Exposure Prophylaxis (PrEP) (2018) For (1) Pre-Exposure HIV Prophylaxis, (2) Post-Exposure HIV Prophylaxis (with raltegravir) or (3) HIV Treatment (with raltegravir) in patients with contraindications for 1st line anti-HIV agents Raltegravir
Epinephrine Injection Devices (both 0.15mg and 0.3mg) Alpha-/Beta- Agonist Epinephrine Injection Devices (2020 Any device, auto-injector or pre-filled syringe
Escitalopram Antidepressant, Selective Serotonin Reuptake Inhibitor SSRIs (2019) Citalopram; Fluoxetine; Paroxetine; Sertraline
Estradiol tablets Estrogen Derivative Menopausal Hormone Therapy (2016)
Estrogen vaginal cream Estrogen Derivative NPTC Meeting Update (May 2018) *Any product* Estradiol tablets
Etanercept -OR- Adalimumab (can choose either product) Antirheumatic, Disease Modifying; Tumor Necrosis Factor (TNF) Blocking Agent TNF Inhibitors (2016) ONLY In consultation with a rheumatologist Adalimumab -OR- Etanercept (can choose either product)
Ethambutol Antitubercular Agent Isoniazid; Pyrazinamide; Rifampin; Rifapentine
Ethinyl estradiol / Etonogestrel vaginal ring Contraceptive; Estrogen and Progestin Combination Contraception (2016)
Ethinyl estradiol / Norelgestromin, transdermal Contraceptive; Estrogen and Progestin Combination Contraception (2016)
Etonogestrel, implant Contraceptive; Progestin Contraception (2016) For use by a skilled and privileged provider Oral contraceptive pill, progestin only
Ezetimibe Antilipemic Agent, 2-Azetidinone 2018 ACC/AHA Cholesterol Guidelines (2019)
Fibric Acid Derivative ===REMOVED from NCF=== Hyperlipidemia (2017) Removed Feb 2017
Finasteride 5 Alpha-Reductase Inhibitor Benign Prostatic Hypertrophy (2016)
Fluoride, oral Nutritional Supplement Supplements in Oral Health (2016) *Any oral formulation*
Fluoxetine Antidepressant, Selective Serotonin Reuptake Inhibitor Sertraline
Fluticasone / Salmeterol (Advair®) ===REMOVED from NCF=== (see immediately below) Removed Oct 2012 Fluticasone/salmeterol
Fluticasone/salmeterol Beta2 Agonist, Long-Acting; Corticosteroid, Inhalant LABAs (2019) Mometasone (Asmanex®)
Folic Acid Vitamin, Water Soluble Supplements in Womens Health (2016) Any product containing >400 mcg / daily dose
Furosemide Antihypertensive; Loop Diuretic Heart Failure Overview (2017)
Gabapentin Anticonvulsant, Miscellaneous; GABA Analog Gabapentin & Pregabalin in Pain (2014)
Gemfibrozil ===REMOVED from NCF=== Dyslipidemia Guidelines Review (2014) Removed Feb 2014
Glecaprevir/pibrentasvir (Mavyret®) Antihepaciviral HCV Treatment (2018) Ledipasvir/sofosbuvir (Harvoni®); Sofosbuvir/velpatasvir (Epclusa®)
Glipizide Antidiabetic Agent; Sulfonylurea Sulfonylureas (2015)
Glucagon Antidote; Hypoglycemia For outpatient use
Glucose, Oral Antidote Glucagon Delivery Devices (2021) Any formulation Glucagon
Glyburide ===REMOVED from NCF=== (see Glipizide) Sulfonylureas (2015) Removed May 2015 Glipizide
H1 Antagonist (2nd generation), long-acting Histamine H1 Antagonist, Second Generation *Any product*
Haloperidol decanoate Antipsychotic, Typical (First Generation) - Injectable Long-Acting Injectable Antipsychotics (2020) Injectable Aripiprazole lauroxil
Hydrochlorothiazide Antihypertensive; Thiazide Diuretic Diuretics (2014) Chlorthalidone
Hydroxychloroquine Antimalarial Non-biologic DMARDs (2016) Leflunomide; Methotrexate; Sulfasalazine
Ibuprofen Nonsteroidal Anti-Inflammatory Drug NSAIDs (2014) Diclofenac; Indomethacin; Meloxicam; Naproxen
Imipramine ===REMOVED from NCF=== (see Nortriptyline) Antidepressant Use in Chronic Pain (2014) Removed May 2014 Nortriptyline
Indomethacin Nonsteroidal Anti-Inflammatory Drug NSAIDs (2014) Diclofenac; Ibuprofen; Meloxicam; Naproxen
Insulin / Regular human (NovoLIN® R) Insulin, Short-Acting Insulins (2015) *Branded product*
Insulin aspart (NovoLog®) Insulin, Rapid-Acting Insulins (2015) *Branded product*; Pen Device
Insulin aspart / Insulin aspart protamine (NovoLog® Mix 70/30) Insulin, Combination (70/30 Mix) Insulins (2015) *Branded product*; Pen Device
Insulin detemir (Levemir®) Insulin, Long-Acting Insulins (2015) *Branded product*; Pen Device Insulin glargine (Lantus®)
Insulin glargine (Lantus®) ===REMOVED from NCF=== (see Insulin detemir) NPTC Meeting Update (May 2019) Removed May 2019 Insulin detemir (Levemir®)
Insulin NPH (NovoLIN® N) Insulin, Intermediate-Acting Insulins (2015) *Branded product*
Insulin NPH / Regular human insulin (NovoLIN® 70/30) Insulin, Combination (70/30 Mix) Insulins (2015) *Branded product*
Intrauterine device, copper Contraceptive Contraception (2016) *Any product*; For use by a skilled and privileged provider Intrauterine device, levonorgestrel
Intrauterine device, levonorgestrel Contraceptive, Progestin Contraception (2016) *Any product*; For use by a skilled and privileged provider Intrauterine device, copper
Ipratropium, MDI ===REMOVED from NCF=== COPD Inhalers (2015) Removed Aug 2015 Albuterol, metered dose inhaler (MDI); Tiotropium (Spiriva®)
Iron, oral Iron Salt Hematologic Supplements (2016) *Any oral formulation*
Isoniazid Antitubercular Agent Ethambutol; Pyrazinamide; Rifampin; Rifapentine
Isosorbide dinitrate ===REMOVED from NCF=== (see Isosorbide mononitrate) Removed Aug 2013 Isosorbide mononitrate
Isosorbide mononitrate Antianginal Agent; Vasodilator Nitroglycerin 0.4 Milligrams; Sublingual; Nitroglycerin patch
Lactulose Ammonium Detoxicant; Laxative, Osmotic Cirrhosis & Complications (2015) Polyethylene glycol
Lamotrigine Anticonvulsant, Miscellaneous Antiepileptics (2014) Carbamazepine; Divalproex; Levetiracetam; Phenytoin; Topiramate
Laxative, bulk-forming Bulk-forming Laxative *Any product*
Laxative, stimulant Stimulant Laxative *Any product*
Ledipasvir/sofosbuvir (Harvoni®) Antihepaciviral HCV Treatment (2018) Glecaprevir/pibrentasvir (Mavyret®); Sofosbuvir/velpatasvir (Epclusa®)
Leflunomide Antirheumatic, Disease Modifying Non-biologic DMARDs (2016) Hydroxychloroquine; Methotrexate; Sulfasalazine
Letrozole Antineoplastic Agent, Aromatase Inhibitor
Levetiracetam Anticonvulsant, Miscellaneous Antiepileptics (2014) Carbamazepine; Divalproex; Lamotrigine; Phenytoin; Topiramate
Levonorgestrel (Plan B One-Step®) Contraceptive, Progestin Contraception (2016) *Branded product* Ulipristal
Levothyroxine Thyroid Agent
Liraglutide or semaglutide Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist GLP-1 Receptor Agonists (2019) Select either of these subcutaneous agents, no preference given
Lisinopril Antihypertensive, Angiotensin-Converting Enzyme Inhibitor ACEIs & ARBs in Heart Failure (2017)
Lithium Antimanic Agent ER Lithium & Divalproex (2012)
Loperamide Antidiarrheal Irritable Bowel Syndrome (2018)
Lopinavir / Ritonavir (Kaletra®) ===REMOVED from NCF=== (see Emtricitabine/tenofovir) HIV PrEP (2018) Removed August 2013 Emtricitabine / Tenofovir (Truvada®) - (**REMS drug**)
Lorazepam Benzodiazepine Alcohol Withdrawal Syndrome (2015) Clonazepam
Losartan Antihypertensive, Angiotensin II Receptor Blocker ACEIs & ARBs in Heart Failure (2017)
Lovastatin ===REMOVED from NCF=== (see Atorvastatin, Pravastatin, Rosuvastatin, Simvastatin) Dyslipidemia Guidelines Review (2014) Removed April 2012 Atorvastatin; Pravastatin; Rosuvastatin; Simvastatin
Low-molecular weight heparin Low-molecular Weight Heparin VTE Prophylaxis (2011) *Any product*
Medroxyprogesterone acetate, injection Contraceptive, Progestin (Injection/Depot) Contraception (2016) Medroxyprogesterone, oral; Oral contraceptive pill, progestin only
Medroxyprogesterone, oral Contraceptive; Progestin Polycystic Ovarian Syndrome (2017) Medroxyprogesterone acetate, injection; Oral contraceptive pill, progestin only
Meloxicam Nonsteroidal Anti-Inflammatory Drug NSAIDs (2014) Diclofenac; Ibuprofen; Indomethacin; Naproxen
Memantine N-Methyl-D-Aspartate (NMDA) Receptor Antagonist
Metformin Antidiabetic Agent; Biguanide
Methimazole Antithyroid Agent; Thioamide Hyperthyroidism (2021) Propylthiouracil
Methotrexate Antineoplastic Agent; Antirheumatic; Disease Modifying; Immunosuppresant Agent Non-biologic DMARDs (2016) Hydroxychloroquine; Leflunomide; Sulfasalazine
Methylphenidate (immediate release) Central Nervous System Stimulant Pediatric use only Methylphenidate (long-acting)
Methylphenidate (long-acting) Central Nervous System Stimulant Pediatric use only Methylphenidate (immediate release)
Metoprolol Antihypertensive; Beta-Blocker, Beta1 Selective Beta-blockers in Heart Failure (2017) Atenolol; Propranolol
Moisturizers (both cream- AND petroleum-based) Skin and Mucous Membrane Agent, Miscellaneous; Topical Skin Product Atopic Dermatitis (2020) Corticosteriods (Topical) - High potency (Class I and II); Corticosteroid (Topical) - Intermediate potency; Corticosteroid (Topical) - Low potency; Tacrolimus
Mometasone (Asmanex®) Corticosteroid, Inhalant *Branded product*
Mometasone / Formoterol (Dulera®) ===REMOVED from NCF=== (see Fluticasone/salmeterol) LABAs (2019) Removed June 2019 Fluticasone/salmeterol
Montelukast Leukotriene Receptor Antagonist
Naloxone Antidote; Opioid Antagonist Treatment of Opioid Overdose (2014)
Naltrexone, extended-release for injection (**REMS drug**) Antidote; Opioid Antagonist Opioid Use Disorder (2018) **See REMS here** Exit Disclaimer: You Are Leaving www.ihs.gov 
Naltrexone, oral Antidote; Opioid Antagonist Alcohol Use Disorders (2015) Naloxone
Naproxen Nonsteroidal Anti-Inflammatory Drug NSAIDs (2014) Diclofenac; Ibuprofen; Indomethacin
Niacin extended release (Niaspan®) ===REMOVED from NCF=== Hyperlipidemia (2017) Removed Feb 2017
Nicotine replacement therapy (NRT), combination Smoking Cessation Aid Nicotine Dependence (2015) Combination NRT (nicotine patches + any short-acting NRT product) Bupropion; Varenicline
Nifedipine (controlled or extended release) ===REMOVED from NCF=== (see Amlodine) Calcium Channel Blockers (2014) Removed August 2014 Amlodipine
Nitroglycerin 0.4 milligrams, sublingual Antianginal Agent; Antidote, Extravasation; Vasodilator Isosorbide mononitrate; Nitroglycerin patch
Nitroglycerin patch Antianginal Agent; Antidote, Extravasation; Vasodilator Isosorbide mononitrate; Nitroglycerin 0.4 milligrams; Sublingual
Nortriptyline Antidepressant, Tricyclic Antidepressants in Pain Mgmt (2014) Amitriptyline
Omeprazole (enteric coated) ===REMOVED from NCF=== (see Proton Pump Inhibitor) Long-Term Use of PPIs (2014) Removed Feb 2014 Proton Pump Inhibitor
Ondansetron Antiemetic; Selective 5-HT3 Receptor Antagonist Antiemetic Agents (2021)
Ophthalmic Prostaglandin Analog Ophthalmic Prostaglandin Analog Ophth Prostaglandin Analogs (2018) *Any product*
Oral contraceptive pill, extended cycle Contraceptive Contraception (2016) *Any product*
Oral contraceptive pill, monophasic: 20mcg EE (low) Contraceptive *Any product* Monophasic: 30-35mcg EE (medium); Oral contraceptive pill
Oral contraceptive pill, monophasic: 30-35mcg EE (medium) Contraceptive *Any product* Monophasic: 20mcg EE (low) ; Oral contraceptive pill
Oral contraceptive pill, progestin only Contraceptive *Any product* Etonogestrel; Implant; Intrauterine Device; Levonorgestrel
Oral contraceptive pill, triphasic Contraceptive *Any product* Monophasics ; Oral Contraceptive Pill
Oseltamivir Antiviral Agent; Neuraminidase Inhibitor Treatment of Influenza (2019)
Oxybutynin, Extended-release Antispasmodic Agent, Urinary Antimuscarinics (2019) Oxybutynin, Immediate-release
Oxybutynin, Immediate-release Antispasmodic Agent, Urinary Antimuscarinics (2019) Oxybutynin, Extended-release
Paroxetine Antidepressant, Selective Serotonin Reuptake Inhibitor SSRIs (2019) Citalopram; Escitalopram; Fluoxetine; Sertraline
Phentermine Central Nervous System Stimulant Obesity Treatment (2018)
Phenytoin Anticonvulsant, Hydantoin Antiepileptics (2014) Carbamazepine; Divalproex; Lamotrigine; Levetiracetam; Topiramate
Phosphodiesterase 5 (PDE5) Inhibitor Phosphodiesterase-5 Enzyme Inhibitor Phosphodiesterase 5 Inhibitors (2018) *Any product*
Pioglitazone Antidiabetic Agent, Thiazolidinedione Thiazolidinediones (2017)
Polyethylene glycol Laxative, Osmotic Irritable Bowel Syndrome (2018) *Any product* Lactulose
Pravastatin Antilipemic Agent, HMG-CoA Reductase Inhibitor Hyperlipidemia (2017) Atorvastatin; Rosuvastatin; Simvastatin
Prazosin Alpha1 Blocker; Antihypertensive PTSD Indication (2012) Doxazosin; Tamsulosin
Prednisone Corticosteroid, Systemic
Propranolol Antihypertensive; Beta-Blocker, Non-Selective Beta Blockers (2014) Atenolol; Metoprolol
Propylthiouracil Antithyroid Agent; Thioamide Hyperthyroidism (2021) Methimazole
Proton Pump Inhibitor Proton Pump Inhibitor GERD & PUD (2018) *Any product*
Pyrazinamide Antitubercular Agent Ethambutol; Isoniazid; Rfapentine ; Rifampin
Pyridoxine (Vitamin B6) Vitamin, Water Soluble Supplements in Obstetrics (2016)
Raltegravir Antiretroviral, Integrase Inhibitor (Anti-HIV) HIV Treatment (2019) For (1) HIV Post-Exposure Prophylaxis (with emtricitabine/ tenofovir DF) or (2) HIV Treatment (with emtricitabine/tenofovir DF) in patients with contraindications for 1st line anti-HIV agents Emtricitabine/tenofovir disoproxil fumarate
Ranitidine* Histamine H2 Antagonist GERD & PUD (2018) *(April 1, 2020) The Food and Drug Administration has recommended that all formulations of ranitidine be taken off the market due to contaminates of N-Nitrosodimethylamine (NDMA), a carcinogen, in ranitidine products. Exit Disclaimer: You Are Leaving www.ihs.gov  Proton Pump Inhibitor
Rifampin Antitubercular Agent Ethambutol; Isoniazid; Pyrazinamide; Rifapentine
Rifapentine Antitubercular Agent Rifapentine (2013) Ethambutol; Isoniazid; Pyrazinamide; Rifampin
Rifaximin Antibiotic, Rifamycin Hepatic Encephalopathy (2020) After failure of, or intolerance to, lactulose monotherapy as indicated for hepatic encephalopathy Lactulose
Rosuvastatin Antilipemic Agent, HMG-CoA Reductase Inhibitor Hyperlipidemia (2017) Atorvastatin; Pravastatin; Simvastatin
Salmeterol (Serevent®) ===REMOVED from NCF=== Inhaled Anticholinergics (2011) Removed Sept 2011
Salsalate Salicylate
Saxagliptin ===REMOVED from NCF=== (see Alogliptin) DPP-IV Inhibitors (2019) Removed Feb 2019 Alogliptin
Semaglutide or liraglutide Antidiabetic Agent, Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist GLP-1 Receptor Agonists (2019) Select either of these subcutaneous agents, no preference given
Serotonin 5-HT1 agonist (Triptan) Antimigraine Agent; Serotonin 5-HT 1B/1D Receptor Agonist Triptans (2016) Any two (2) triptan medications are required, one must be sumatriptan Sumatriptan
Sertraline Antidepressant, Selective Serotonin Reuptake Inhibitor Citalopram; Escitalopram; Fluoxetine; Paroxetine
Sevelamer carbonate Phosphate Binder Phosphate Binders (2018) For patients on dialysis who cannot use calcium-based phosphate binders due to hypercalcemia Calcium
Simvastatin Antilipemic Agent, HMG-CoA Reductase Inhibitor Dyslipidemia Guideline Review (2014) Atorvastatin; Pravastatin; Rosuvastatin
Sofosbuvir/velpatasvir (Epclusa®) Antihepaciviral HCV Treatment (2018) Glecaprevir/pibrentasvir (Mavyret®); Ledipasvir/sofosbuvir (Harvoni®)
Spironolactone Antihypertensive; Mineralocorticoid Receptor Antagonists; Potassium Sparing Diuretic Mineralocorticoid Receptor Antagonist in HF (2017)
Sulfasalazine 5-Aminosalicylic Acid Derivative Hydroxychloroquine; Leflunomide; Methotrexate
Sulindac ===REMOVED from NCF=== (see Diclofenac, Ibuprofen, Indomethacin, Meloxicam, Naproxen) NSAIDs in Chronic Pain (2014) Removed May 2014 Diclofenac; Ibuprofen; Indomethacin; Meloxicam; Naproxen
Sumatriptan Antimigraine Agent; Serotonin 5-HT 1B/1D Receptor Agonist Triptans (2016) Any two (2) triptan medications are required, one must be sumatriptan
Tacrolimus Calcineurin Inhibitor; Immunosuppressant Agent; Topical Skin Product Atopic Dermatitis (2020) Corticosteriods (Topical) - High potency (Class I and II); Corticosteroid (Topical) - Intermediate potency; Corticosteroid (Topical) - Low potency; Moisturizers (both cream- AND petroleum-based)
Tamoxifen Antineoplastic Agent, Estrogen Receptor Antagonist; Selective Estrogen Receptor Modulator
Tamsulosin Alpha1 Blocker Benign Prostatic Hypertrophy (2016) Doxazosin; Prazosin
Terazosin ===REMOVED from NCF=== (see Doxazosin, Prazosin, Tamsulosin) Prazosin in PTSD (2012) Removed Jan 2012 Doxazosin; Prazosin; Tamsulosin
Tiotropium (Spiriva®) Long-Acting Anticholinergic Agent Inhaled Anticholinergics (2011) *Branded product*
Topiramate Anticonvulsant, Miscellaneous Antiepileptic Medications (2014) Carbamazepine; Divalproex; Lamotrigine; Levetiracetam; Phenytoin
Trazodone ===REMOVED from NCF=== Insomnia (2015) Removed Oct 2015
Tretinoin, topical Topical Skin Product, Acne Acne (2013) *Any product*
Trospium ===REMOVED from NCF=== (see Oxybutynin ER, IR) Antimuscarinics (2019) Removed Feb 2019 Oxybutynin, Extended-release; Oxybutynin, Immediate-release
Ulipristal Contraceptive; Progestin Receptor Modulator Contraception (2016) Levonorgestrel (Plan B One-Step®)
Umeclidinium/vilanterol Long-Acting Muscarinic Antagonist (LAMA) / Long-Acting Beta2 Agonist (LABA) LAMAs (2019) Tiotropium (Spiriva®)
Vaccines, All ACIP-recommended Vaccines Vaccine (2011) All ACIP recommended vaccines for routine use in accordance with ACIP guidelines
Varenicline Partial Nicotine Agonist, Smoking Cessation Aid Nicotine Dependence (2015) Bupropion
Venlafaxine Antidepressant, Serotonin/Norepinephrine Reuptake Inhibitor/Antagonist SNRIs (2012) Bupropion; Duloxetine
Verapamil ===REMOVED from NCF=== (see Diltiazem) Calcium Channel Blockers (2014) Removed August 2014 Diltiazem
Vitamin D Vitamin D Analog Vitamin D (2010) *Any product*
Vitamin D Analog (Topical) Vitamin D Analog Psoriasis (2018) *Any product*
Warfarin Anticoagulant; Vitamin K Antagonist Direct Oral Anticoagulants (2017) Apixaban; Low-molecular weight heparin