Recommendations for Aspirin and Other Antiplatelet Therapy
Prescribe aspirin 75-162 mg in patients with or without diabetes who have a history of atherosclerotic cardiovascular disease (ASCVD*), unless contraindicated.
Consider clopidogrel 75mg daily, if allergic to aspirin.
Consider aspirin 75-162 mg in patients with diabetes and:
An increased risk of atherosclerotic cardiovascular disease (ASCVD*) (e.g., age 50-70 years and one or more risk factors**); and
Not at increased risk for bleeding
* ASCVD is atherosclerosis affecting the vasculature that results in diseases of any of the following: the heart (e.g., myocardial infarction, angina), the brain (e.g., stroke, transient ischemic attack), and the lower extremities (e.g., peripheral artery disease, limb ischemia).
** Risk factors include: family history of premature ASCVD, hypertension, dyslipidemia, smoking, chronic kidney disease, or albuminuria.
Clinician and Educator Resources
Featured Aspirin and Other Antiplatelet Therapy Resources